Evelyn Guevara1, Jukka U. Palo1, Jonathan L. King 2, Maria Geppert3, Frank R. Wendt2, Monika Stoljarova2, Sonia Guillén4, Lutz Roewer3, Bruce Budowle2 and Antti Sajantila1
2 Institute of Applied Genetics, Department of Molecular and Medical Genetics, University of North Texas Health Science Center, Fort Worth, TX, USA
3 Institute of Legal Medicine and Forensic Sciences, Department of Forensic Genetics, Charité – Universtätsmedizin Berlin, Berlin, Germany
4 Centro Mallqui, Institute of Bioarchaeology, Peru
Our research focuses on the origin and population history of the human communities that inhabit the cloud forests of northeastern Peru, with both contemporary and ancient DNA data. Here we report preliminary results and conclusions from the study of the contemporary genetic diversity. Previously, we used 23 Y-chromosomal STRs and mtDNA sequence (HVR1 and HVR2) data from four populations: Chachapoya, Huancas, Jivaro and Cajamarca. Both lineage marker data showed high levels of genetic diversity for all populations, especially in the Chachapoya (e.g. h=0.9974±0.0032/ Y-chromosome). Interestingly, this population also shows signatures of population expansion for both markers such as unimodal mismatch distribution pattern, large Tajima’s D (D=-1.51132, p=0.0309) and Fu’s Fs (Fs=-23.98616, p=0.0018) values. Additionally, in Neighbor-Joining trees, the Chachapoya assumes a basal position among most South American populations (1). This evidence points to a complex and distinctive past demographic history in the region.
To deepen our understanding on various demographic processes in this area, located in the juncture of two major ecosystems, the Andes and the lush Amazon, we have produced a subset of whole mtDNA (N=162) and Y-SNP (N=110) data, which is currently being analyzed in a population genetic framework. This will allow us e.g. to make haplogroup assignments more accurately, but more importantly, it will serve to test several hypotheses such us the existence of a constant effective population size (Ne) through time in the Chachapoya. This and other questions of population genetic interest, in a region of South America little explored until now, will be addressed in this presentation.
Guevara E.K., Palo Jukka U., Guillen Sonia and Antti Sajantila. MtDNA and Y-chromosomal diversity in the Chachapoya, a population from the northeast Peruvian Andes-Amazon divide. American Journal of Human Biology 2016; 28(6):857-867. DOI: 10.1002/ajhb.22878.